At HKI, there are two groups dedicated to Systems Biology (www.sysbio.hki-jena.de).

These Groups represents the Institute in the Jena Centre for Bioinfomatics.

The Research Group Systems Biology /Bioinformatics (headed by Prof. Dr. Reinhard Guthke) is one of these two groups.

Mission:

The goal in systems biology and bioinformatics is to discover structures and to understand the dynamics of biological systems by data-based and purpose-driven modeling. Systems biological research at the HKI is dedicated to the integrated analysis of transcriptome and proteome as well as microbiological and clinical data. Data analysis comprises storage and management of heterogeneous experimental data in a data warehouse, data pre-processing, discovery of the main features and patterns and – finally – generation of testable model hypotheses. The hypotheses have been embedded in predictive mathematical and computational models that represent
(i) the available expert knowledge,
(ii) facts extracted from biological databases and
(iii) the hypotheses generated by experimental data analysis.
The data analysis pipeline at the HKI is focused on the generation of quantitative dynamic and/or qualitative temporal models that are generated from time series data by dynamic data mining techniques. Some of these techniques have been developed – in collaboration with other groups – by our own work.

GCB2012 Jena, 19-22 September 2012
http://www.gcb2012-jena.de