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Microbial Pathogenicity Mechanisms
Publications

 

ORIGINAL PUBLICATIONS
 
2004 - 2010

 

2010
 
Wilson D, Hube B (2010) Hgc1 mediates dynamic Candida albicans-endothelium adhesion events during circulation. Eukaryotic Cell 9, 278-287. [PubMed]

Cheng SC, Chai LY, Joosten LA, Vecchiarelli A, Hube B, Van Der Meer JW, Kullberg BJ, Netea MG (2010) Candida albicans releases soluble factors that potentiate cytokine production by human cells through a protease-activated receptor 1- and 2-independent pathway. Infect Immun 78, 393-399. [PubMed]

Hummert S, Hummert C, Schröter A, Hube B, Schuster S (2010) Game theoretical modelling of survival strategies of Candida albicans inside macrophages. J Theor Biol 264: 312-318. [PubMed]

Brunke S, Seider K, Almeida RS, Heyken A, Fleck CB, Brock M, Barz D, Rupp S, Hube B (2010) Candida glabrata tryptophan-based pigment production via the Ehrlich pathway. Mol Microbiol 76: 25-47. [PubMed]

Jacobsen ID, Brunke S, Seider K, Schwarzmüller T, Firon A, d'Enfért C, Kuchler K, Hube B (2010) Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy. Infect Immun 78: 1066-1077. [PubMed]

Jacobsen ID, Große K, Slesiona S, Hube B, Berndt A, Brock M. (2010) Embryonated eggs as an alternative infection model to investigate Aspergillus fumigatus virulence. Infect Immun 78: 2995-3006. [PubMed]

Dalle F, Wächtler B, L'Ollivier C, Holland G, Bannert N, Wilson D, Labruère C, Bonnin A, Hube B (2010) Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes. Cell Microbiol 12: 248-271. [PubMed]

Gehrke A, Heinekamp T, Jacobsen ID, Brakhage AA (2010) Heptahelical receptors GprC and GprD of Aspergillus fumigatus are essential regulators of colony growth, hyphal morphogenesis and virulence. Appl Environ Microbiol 76: 3989-3998. [PubMed]

Schöbel F, Jacobsen ID, Brock M (2010) Evaluation of lysine biosynthesis as antifungal drug target: Biochemical characterization of Aspergillus fumigatus homocitrate synthase and virulence studies. Eukaryot Cell 9: 878-893. [PubMed]

Menger B, Vogt PM, Jacobsen ID, Allmeling C, Kuhbier JW, Mutschmann F, Reimers K (2010) Resection of a large intra-abdominal tumor in the Mexican axolotl: a case report. Vet Surg 39: 232-233. [PubMed]

Schmidt A, Wächtler B, Temp U, Krekling T, Séguin A, Gershenzon J (2010) A bifunctional geranyl and geranylgeranyl diphosphate synthase is involved in terpene oleoresin formation in Picea abies. Plant Physiol 152: 639-655. [PubMed]

Pietrella D, Rachini A, Pandey N, Schild L, Netea M, Bistoni F, Hube B, Vecchiarella A (2010) Inflammatory response induced by aspartic proteases of C. albicans is independent from proteolytic activity. Infection and Immunity, accepted.

 

2009
 

Dalle F, Wächtler B, L’Ollivier C, Holland G, Bannert N, Wilson D, Labruère C, Bonnin A, Hube B (2009) Cellular interactions of Candida albicans with human oral epithelial cells and enterocytes. Cellular Microbiology 12: 248-271. [PubMed]

Voelksch B, Thon S, Jacobsen I D, Gube M (2009) Polyphasic study of plant- and clinic-associated Pantoea agglomerans strains reveals indistinguishable virulence potential. Infection, Genetics and Evolution 9: 1381-1391. [PubMed]

Hornbach A, Heyken A, Schild L, Hube B, Löffler J, Kurzai O (2009) Secreted aspartic protease Sap9 modulates the interaction of Candida albicans with human neutrophils. Infection and Immunity 77: 5216-5224. [PubMed]

Schaller M, Weindl G, Hube B (2009) Introduction: host responses. Methods Mol Biol 470: 291-292. [PubMed]

Gropp K, Schild L, Schindler , Hube B, Zipfel PF, Skerka C (2009) The yeast Candida albicans evades the human complement system by secretion of aspartic proteinases. Molecular Immunology 47: 465-475. [PubMed]

Laube T, Bernet A, Dahse HM, Jacobsen ID, Seifert K (2009) Synthesis and pharmacological activities of some sesquiterpene quinones and hydroquinones. Bioorg Med Chem 17: 1422-1427. [PubMed]

Domin N, Wilson D, Brock M (2009) Methylcitrate cycle activation during adaptation of Fusarium solani and Fusarium verticillioides to propionyl-CoA generating carbon sources. Microbiology 155: 3903-3912. [PubMed]

Butler G, Rasmussen MD, Lin MF, Santos MAS, Sakthikumar S, Munro CA, Rheinbay E, Grabherr M, Forche A, Reedy JL, Agrafioti I, Arnaud MB, Bates S, Brown AJP, Brunke S, Costanzo MC, Fitzpatrick DA, de Groot PWJ, Harris D, Hoyer LL, Hube B, Klis FM, Kodira C, Lennard N, Logue ME, Martin R, Neiman AM, Nikolaou E, Quail MA, Quinn J, Santos MC, Schmitzberger FF, Sherlock G, Shah P, Silverstein K, Skrzypek MS, Soll D, Staggs R, Stansfield I, Stumpf MPH, Sudbery PE, Thyagarajan S, Zeng Q, Berman J, Berriman M, Heitman J, Gow NAR, Lorenz MC, Birren BW, Kellis M,Cuomo CA (2009) Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature 459: 657-662. [PubMed]

Meiller TF, Hube B, Schild L, Shirtliff ME, Scheper MA, Winkler R, Ton A, Jabra-Rizk MA (2009) A novel immune evasion strategy of Candida albicans: proteolytic cleavage of a salivary antimicrobial peptide. PLoS ONE 4: e5039.

Wilson D, Thewes S, Zakikhany K, Fradin C, Albrecht A, de Almeida R, Brunke S, Martin R, Mayer F, Schild L, Seider K, Waechtler B, Jacobsen I, Hube B (2009) Identifying infection-associated genes of Candida albicans in the post genomic era. FEMS Yeast Research 9: 688-700. [PubMed]

Hort W, Lang S, Brunke S, Mayser P, Hube B (2009) Analysis of differentially expressed genes associated with tryptophan-dependent pigment synthesis in M. furfur by cDNA subtraction technology. Med Mycol 47: 248-258. [PubMed]

Hube B (2009) Fungal adaptation to the host environment. Current Opinion in Microbiology 12: 1-3.

Almeida RS, Wilson D, Hube B (2009) Candida albicans iron acquisition within the host. FEMS Yeast Res 9: 1000-1012.

 

2008
 
Hennig-Pauka, I., Baltes, N., Jacobsen, I., Stratmann-Selke, J., Gerlach, G.F., Selbitz, H.J., Waldmann, K.H. (2008) Study of the virulence of Actinobacillus pleuropneumoniae in finishing pigs as a basis for vaccination development. Berl Munch Tierarztl Wochenschr 121: 189-197. [PubMed]

Wozniok, I., Hornbach, A., Schmitt, C., Frosch, M., Einsele, H., Hube, B., Löffler, J., Kurzai, O. (2008) Induction of ERK kinase signalling triggers morphotype specific killing of Candida albicans filaments by human neutrophils. Cellular Microbiology 10: 807-820. [PubMed]

Schrettl, M., Kim, H.S., Eisendle, M., Kragl, C., Nierman, W.C., Heinekamp, T., Werner, E.R., Jacobsen, I., Illmer, P., Yi, H., Brakhage, A.A., Haas, H. (2008) SreA-mediated iron regulation in Aspergillus fumigatus. Mol Microbiol 70: 27-43. [PubMed]

Mora-Montes, H.M., Bader, O., López-Romero, E., Zinker, S., Ponce-Noyola, P., Hube, B., Gow, N.A.R., Flores-Carreón, A. (2008) Kex2 protease converts the endoplasmic reticulum α1,2-mannosidase of Candida albicans into a soluble cytosolic form. Microbiology 154: 3782-3794. [PubMed]

Hort, W., Lang, S., Brunke, S., Mayser, P., Hube, B. (2008) Analysis of differentially expressed genes associated with tryptophan-dependent pigment synthesis in M. furfur by cDNA subtraction technology. Med Mycol 25: 1-11 [PubMed].

Bader, O., Krauke, Y., Hube, B. (2008) Processing of predicted substrates of fungal Kex2 proteinases from Candida albicans, C. glabrata, Saccharomyces cerevisiae and Pichia pastoris. BMC Microbiol 8: 116. [PubMed]

Naglik, J.R., Moyes, D., Makwana, J., Kanzaria, P., Tsichlaki, E., Weindl, G., Tappuni, A.R., Rodgers, C.A., Woodman, A.J., Challacombe, S.J., Schaller, M., Hube, B. (2008) Quantitative expression of the Candida albicans secreted aspartyl proteinase gene family in human oral and vaginal candidiasis. Microbiology 154: 3266-3280. [PubMed]

Almeida, R.S., Brunke, S., Albrecht, A., Thewes, S., Laue, M., Edwards, J.E., Filler, S.G. Jr., Hube, B. (2008) The hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin. PLoS Pathogens 4: e1000217.[PubMed] [PLoS]

Thewes, S., Moran, G.P., Magee, B.B., Schaller, M., Sullivan, D.J., Hube, B. (2008) Phenotypic screening, transcriptional profiling, and comparative genomic analysis of an invasive and non-invasive strain of Candida albicans. BMC Microbiology 8: 187. [PubMed]

Valiante, V., Heinekamp, T., Jain, R., Härtl, A., Brakhage, A.A. (2008) The mitogen-activated protein kinase MpkA of Aspergillus fumigatus regulates cell wall signaling and oxidative stress response. Fungal Genet Biol 45: 618-627. [PubMed]

Ozegowski JH, Presselt N, Härtl A, Bocker T, Sänger J, Schmidt A, Willing K, Müller PJ. (2008) Anti-atherosclerotic effect of microbial hyaluronate lyase from group B streptococci. Pharmazie 63: 601-605. [link]

Mota Júnior AO, Malavazi I, Soriani FM, Heinekamp T, Jacobsen I, Brakhage AA, Savoldi M, Goldman MH, da Silva Ferreira ME, Goldman GH (2008) Molecular characterization of the Aspergillus fumigatus NCS-1 homologue, NcsA. Mol Genet Genomics 280: 483-495. [PubMed]


 

2004-2007
 
2007

Thewes, S., Reed, H.-K., Grosse-Siestrup, Ch., Groneberg, D.A., Meissler, M., Schaller, M., Hube, B. (2007) Haemoperfused liver as an ex vivo model for organ invasion of Candida albicans. Journal of Medical Microbiology 561: 266-270. [PubMed]

Kunze, D., MacCallum, D., Odds, F.C., Hube, B. (2007) Multiple functions of DOA1 in Candida albicans. Microbiology 153: 1026-1041. [PubMed]

Fradin, Ch., Mavor, A.L., Weindl, G., Schaller, M., Hanke, K., Kaufmann, St., Mollenkopf, H., Hube, B. (2007) The early transcriptional response of human granulocytes to infection with Candida albicans is not essential for killing, but reflects cellular communications. Infection and Immunity 75: 1493-1501. [PubMed]

Eckert, S.E., Heinz, W.J., Zakikhany, K., Thewes, S., Haynes, K., Hube, B., Mühlschlegel, F.A. (2007) PGA4, a GAS homologue from Candida albicans, is up-regulated early in infection processes. Fungal Genetics and Biology 44: 368-377. [PubMed]

Thewes, S., Kretschmar, M., Park, H., Schaller, M., Filler, S., Hube, B. (2007) In vivo and ex vivo comparative transcriptional profiling of invasive and non-invasive isolates identifies genes associated with tissue invasion. Candida albicans. Molecular Microbiology 63: 1606-1628. [PubMed]

da Silva Ferreira, M.E., Heinekamp, T., Härtl, A., Brakhage, A.A., Semighini, C.P., Harris, S.D., Savoldi, M., Goldman, M.H., Goldman, G.H. (2007) Functional characterization of the Aspergillus fumigatus calcineurin. Fungal Genetics and Biology 44: 219-230. [PubMed]

Gebhardt, P., Dornberger, K., Gollmick, F.A., Gräfe, U., Härtl, A., Görls, H., Schlegel, B., Hertweck, C. (2007) Quercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill). Bioorganic & Medicinal Chemistry Letters 17: 2558-2560. [PubMed]

Zakikhany, K., Naglik, J.R., Schmidt-Westhausen, A., Holland, G., Schaller, M., Hube, B. (2007) In vivo transcript profiling of Candida albicans identifies a gene essential for interepithelial dissemination. Cellular Microbiology 9: 2938-2954. [PubMed]

Jackson, B.E., Wilhelmus, K.R., Hube, B. (2007) The role of secreted aspartyl proteinases in Candida albicans keratitis. Invest Ophthalmol Vis Sci 48: 3559-3565. [PubMed]

Weindl, G., Naglik, J.R., Kaesler, S., Biedermann, T., Hube, B., Korting, H.C., Schaller, M. (2007) Epithelial cells establish direct antifungal defense through toll-like receptor 4-mediated signaling. Journal of Clinical Investigation 117: 3664-3672. [PubMed]

Lessing, F., Kniemeyer, O., Wozniok, I., Loeffler, J., Kurzai, O., Härtl, A., Brakhage, A.A. (2007) The Aspergillus fumigatus transcriptional regulator AfYap1 represents the major regulator for defence against reactive oxygen species but is dispensable for pathogenicity in an intranasal mouse infection model. Eukaryotic Cell 6: 2290-2302. [PubMed]

Ivanova, V., Kolarova, M., Aleksieva, K., Dornberger, K.J., Härtl, A., Moellmann, U., Dahse, H.M., Chipev, N. (2007) Sanionins: anti-inflammatory and antibacterial agents with weak cytotoxicity from the Antarctic moss Sanionia georgico-uncinata. Prep Biochem Biotechnol 37: 343-352. [PubMed]

Keller, S., Helbig, D., Härtl, A., Jahreis, G. (2007) Nanoscale and customary non-esterified sitosterols are equally enriched in different body compartments of the guinea pig. Mol Nutr Food Res 51: 1503-1509. [PubMed]

Jütten P, Schumann W, Härtl A, Dahse HM, Gräfe U. (2007) Thiosemicarbazones of formyl benzoic acids as novel potent inhibitors of estrone sulfatase. J Med Chem 50: 3661-3666. [PubMed]

2006

Albrecht, A., Felk, A., Pichova, I., Naglik, J.R., Schaller, M., de Groot, P., MacCallum, D., Odds, F.C., Schäfer, W., Klis, F., Monod, M., Hube, B. (2006) GPI-anchored proteases of Candida albicans affect cellular processes and host-pathogen interactions. Journal of Biological Chemistry 281: 688-694. [PubMed]

Schaller, M., Zakikhany, K., Naglik, J.R., Weindl, G., Hube, B. (2006) Models of oral and vaginal candidiasis based on in vitro reconstituted human epithelia. Nature Protocols 6: 2767-2773. [Nature Protocols]

Sigle, H.C., Schäfer-Korting, M., Korting, H.C., Hube, B., Niewerth, M. (2006) Investigations on the mode of action of the hydroxypyridone antimycotics rilopirox and piroctone on Candida albicans. Mycoses 49: 159-168. [PubMed]

Neuhof, T., Seibold, M., Thewes, S., Laue, M., Han, C.-O., Hube, B., von Döhren, H. (2006) Comparison of susceptibility and transcription profile of the new antifungal hassallidin A with caspofungin. Biochemical and Biophysical Research Communications 349: 740-749. [PubMed]

Brunke, S., Hube, B. (2006) MfLIP1, a gene encoding an extracellular lipase of the lipid-dependent fungus Malassezia furfur. Microbiology 152: 547-554. [PubMed]

Mrestani, Y., Härtl, A., Neubert, R.H.H. (2006) Influence of absorption enhancers on the pharmacokinetic properties of non-oral ß-lactam-cefpirom using rabbit (Chinchilla) in vivo model. Int J Pharm 309: 67-70.
[PubMed]

Sugareva, V., Brock, M., Härtl, A., Hübner, K., Rhode, M., Heinekamp, T., Brakhage, A.A. (2006) Characterisation of the laccase-encoding gene abr2 of the dihydroxynaphthalene-like melanin gene cluster and its contribution to virulence of Aspergillus fumigatus. Arch Microbiology 186: 345-355. [PubMed]

Kraft, J., Hanske, L., Möckel, P., Zimmermann, S., Härtl, A., Kramer, J.K.G., Jahreis, G. (2006) The conversion efficiency of trans-11 and trans-12 18:1 by Δ9-desaturation differs in rats. J. Nutr 136: 1209-1214. [PubMed]

Wangun, H. V., Härtl, A., Kiet, T.T., Hertweck, C. (2006) Inotilone and related phenylpropanoid polyketides from inonotus sp. and their identification COX and XO inhibitors. ChemBioChem 7:37-39. [PubMed]

Franke, K., Nguyen, M., Härtl, A., Dahse, H.-M., Vogl, G., Würzner, R., Zipfel, P.F., Künkel, W., Eck, R. (2006) The vesicle transport protein Vac1p is required for virulence of Candida albicans. Microbiology 152: 3111-3121. [PubMed]

Hellwage, J., Eberle, F., Babuke, T., Seeberger, H., Richter, H., Kunert, A., Härtl, A., Zipfel, P.F., Jokiranta, T.S., Jozsi, M. (2006) Two factor H related proteins from the mouse: expression analysis and functional characterization. Immunogenetics 58: 883-893. [PubMed]

da Silva Ferreira, M.E., Kress, M.R., Savoldi, M., Goldman, M.H., Härtl, A., Heinekamp, T., Brakhage, A.A., Goldman, G.H. (2006) The akub (KU80) mutant deficient for nonhomolgous end joining is a powerful tool for analyzing pathogenicity in Aspergillus fumigatus. Eukaryot Cell 5: 207-211. [PubMed]

Sauerbrei, A., Härtl, A., Brandstädt, A., Schmidtke, M., Wutzler, P. (2006) Utilization of the embryonated egg for in vivo evaluation of the anti-influenza virus activity of neuraminidase inhibitors. Med Microbiol Immunol 195: 65-71. [PubMed]

2005

D’Enfert, C., Goyard, S., Rodriguez-Arnaveilhe, S., Frangeul, L., Jones, L, Tekaia, F., Bader, O., Albrecht, A., Castillo, L., Dominguez, A., Ernst, J., Fradin, C., Gaillardin, C., Garcia-Sanchez, S., de Groot, P., Hube, B., Klis, F.M., Krishnamurthy, S., Kunze, D., Lopez, M.-C. , Mavor, A., Martin, N., Moszer, I., Onésime, D., Perez Martin J., Sentandreu, R., Valentin, E., Brown, A.J.P. (2005) CandidaDB: A genome database for Candida albicans pathogenomics. Nucleic Acid Research 33: D353-D357. [PubMed]

Schaller, M., Korting, H.C., Borelli, C., Hamm, G., Hube, B. (2005) Candida albicans secreted aspartic proteinases (Sap) modify the epithelial cytokine response in an in vitro model of vaginal candidiasis. Infection and Immunity 73: 2758-2765. [PubMed]

Fradin, C., De Groot, P., MacCallum, D., Schaller, M., Klis, F., Odds, F.C., Hube, B. (2005) Granulocytes govern the transcriptional response, morphology and proliferation of Candida albicans in human blood. Molecular Microbiology 56: 397-415. [PubMed]

Sigle, H. C., Thewes, S., Niewerth, M., Korting, H. C., Schäfer-Korting, M., Hube, B. (2005) Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans. Journal of Antimicrobial Chemotherapy 55: 663-673. [PubMed]

Copping, V. M. S., Barelle, C. J., Hube, B., Gow, N. A. R., Brown, A. J. P., Odds, F. C. (2005) Exposure of Candida albicans to antifungal agents affects expression of SAP2 and SAP9 secreted proteinase genes. Journal of Antimicrobial Chemotherapy 55: 645-654. [PubMed]

Kunze, D., Melzer, I., Bennett, D., Sanglard, D., MacCallum, D., Nörskau, J., Coleman, D.C., Odds, F.C., Schäfer, W., Hube, B. (2005) Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans. Microbiology 151: 3381-3394. [PubMed]

Johne, S., Watzke, R., Meusel, W., Möllmann, U., Härtl, A., Dahse, H.-M., Seifert, K. (2005) Biotechnological production and bioactivities of mollisin and two new, structurally related fungal naphthoquinone metabolites. Chemistry & Biodiversity Vol 2: 1109-1115. [PubMed]

Günther, J., Nguyen, M., Härtl, A., Künkel, W., Zipfel, P.F., Eck, R. (2005) Generation and functional in vivo characterization of a lipid kinase defective phosphatidylinositol Vps34p of Candida albicans. Microbiology 151: 81-89. [PubMed]

Poltermann, S., Nguyen, M., Günther, J., Wendland, J., Härtl, A., Künkel, W., Zipfel, P.F., Eck, R. (2005) The putative vacuolar ATPase subunit Vma7p of Candida albicans is involved in vacuole acidification, hyphal development, and virulence. Microbiology 151: 1645-1655. [PubMed]

2004

Moran, G., Stokes, C., Thewes, S., Hube, B., Coleman, D., Sullivan, D. (2004) Comparative genomics using Candida albicans DNA microarrays reveals absense and divergence of virulence associated genes in Candida dubliniensis. Microbiology 150: 3363-3382. [PubMed]

Schaller, M., Boeld, U., Oberbauer, S., Hamm, G., Hube, B., Korting, H. C. (2004) Protective role and cytokine response of polymorphonuclear leukocytes (PMNs) during transepithelial migration into an in vitro model of oral candidiasis. Microbiology 150: 2807-2813. [PubMed]

Härtl, A., Sauerbrei, A., Stelzner, A., Wutzler, P. (2004) Influenza infection of the embryonated hen’s egg. Drug Research/Arzneimittelforschung 54: 130-134. [PubMed]

Härtl, A., Sauerbrei, A., Stelzner, A., Wutzler, P. (2004) Influenza infection of the embryonated hen’s egg – an alternative model for in vivo evaluation of antiviral compounds. ALTEX 21: 156-157. [PubMed]

 

REVIEWS
 
2009

Hube B (2009) Fungal adaptation to the host environment. Current Opinion in Microbiology 12: 1-3.

Almeida RS, Wilson D, Hube B (2009) Candida albicans iron acquisition within the host. FEMS Yeast Research 9: 1000-1012. [PubMed]

Wilson D, Thewes S, Zakikhany K, Fradin C, Albrecht A, Almeida R, Brunke S, Grosse K, Martin R, Mayer F, Leonhardt I, Schild L, Seider K, Skibbe M, Slesiona S, Waechtler B, Jacobsen I, Hube B (2009) Identifying infection-associated genes of Candida albicans in the post genomic era. FEMS Yeast Research 9: 688-700. [PubMed]

2008

Hube B (2008) Candida, Proteasen und Gene. Mycoses 51: 22-25. [PubMed]

Hube B (2008) Was Candida wild macht. Ärztliche Praxis DermatologieAllergologie 5: 42-43.

Schaller M, Zakikhany K, Weindl G, Borelli C, Korting HC, Hube B (2008) In-vitro-Modelle auf der Basis von rekonstituierter humaner Haut/Schleimhaut zur Charakterisierung der Interaktion zwischen C. albicans und Wirtszellen. Der Hautarzt, Vol. 59 (12)/ Dez 2008.

Zakikhany K, Thewes S, Wilson D, Martin R, Albrecht A, Hube B (2008) From attachment to invasion: Infection associated genes of Candida albicans. Nippon Ishinkin Gakkai Zasshi 49: 245-251. [PubMed]

Hube B (2008) Report on FunNet2007: Forschung an humanpathogenen Pilzen bündeln und koordinieren. The first joint meeting of research consortia on fungal pathogens in Europe 2007, Gosau (Austria), 12.-15. September 2007. Biospektrum 1: 102. [Biospektrum]

Thewes S, Hube B (2008) Untersuchungen zur Invasivität von Candida albicans. Robert Koch-Institut Berlin, Epidemiologisches Bulletin 29: 230-231. [RKI]

2007

Hube B (2007) Report on FunNet2007: Focussing and coordinating European research on human pathogenic fungi. The first joint meeting of research consortia on fungal pathogens in Europe 2007, Gosau (Österreich), 12.-15. September 2007. Mycology Newsletter 1: 23.

2006


Fradin C, Hube B (2006) Transcriptional profiling of Candida albicans in human blood. Microbe/ASM News 1: 76-80. [ASM]

Hube B (2006) Infections associated genes of Candida albicans. Future Microbiology 1: 209-218. [PubMed]

Kaplanek P, de Boer A, Gross U, de Groot P, Hube B, Weig M (2006) Candida and Candidosis today: where are we, and where to go? Meeting report on the Interdisciplinary Forum on Candidosis (IFOCAN), Goettingen, Germany, 23.-25.09.2005. FEMS-Yeast Res. 6: 1290-1294. [PubMed]

2005

Mavor A, Thewes S, Hube B (2005) Systemic fungal infections caused by Candida species: Epidemiology, infection process and virulence attributes. The Journal of Current Drug Targets 6: 863-874. [PubMed]

Schaller M, Borelli C, Korting HC, Hube B (2005) Hydrolytic enzymes as virulence factors of  Candida albicans. Mycoses 48: 365-377. [PubMed]

2004

Hube B (2004) From commensal to pathogen: stage and tissue specific gene expression of Candida albicans. Current Opinion in Microbiology 7: 1-6. [PubMed]

Naglik J, Albrecht A, Bader O, Hube B (2004) Candida proteinases and host/pathogen interactions. Cellular Microbiology 6: 915-926. [PubMed]

Fradin C, Thewes S, Zakikhany K, Albrecht A, Bader O, Kunze D, Hube B (2004) Transcriptional profiling of Candida albicans during infections. Mikologia Lekarska 11: 157-163.

Schaller M, Hube B (2004) Candida albicans-Infektionsmodelle. Bioforum 11/2004: 2-3.

 

BOOK ARTICLES
 
Naglik JR, Hube B (2009) Chapter 9: “Secreted Candida proteins: pathogenicity and host immunity” In: Handbook of pathogenic yeasts (Eds. Bignell E, Ashbee R), p. 97-120.

Schaller M, Weindl G, Hube B (2009) Introduction: host responses. Methods Mol Biol 470, 291-292.

Munro C, Fradin C Bader O, Hube B (2006) Postgenomic approaches to analyse Candida albicans pathogenicity in The Mycota, Vol. XII (“Fungal Genomics and Proteomics”) edited by A. Brown (Hrsg. Springer Verlag). Chapter 9, page 163-184.

Schaller M, Korting HC, Hube B (2004) Virulence factors that promote invasion of Candida albicans. In: Gioconda San-Blas and Richard A. Calderone eds. „Pathogenic Fungi: Host Interactions and Emerging Strategies for Control“. Caister Academic Press. Chapter 3, page 97-127.

 

BOOKS
 
D’Enfert, C., Hube, B. (Eds.) (2007) Candida: Comperative and Functional Genomics. Horizon Bioscience; Caister Academic Press.