The research of the HKI Bio Pilot Plant is mainly focused on the development, optimization and scale-up of biotechnological processes from flask cultures via laboratory scale to pilot scale.
The team of the HKI Bio Pilot Plant is experienced in strain improvement, cultivation and fermentation of a large variety of prokaryotic and eukaroytic microorganisms. This includes genetic engineering of strains to optimize their productivity and to monitor specific physiological parameters during fermentation processes.
State-of-the-art analytical methods as well as techniques and equipment for down­stream processing and purification of low molecular weight natural products, bio­polymers and proteins are available.
Our research strategy is characterized by a highly interdisciplinary approach closely linking microbial physiology, genetic engineering and bioprocess engineering. Expe­rimental and theoretical methods are combined to analyse and control high perfor­mance fermentations considering the physiological requirements of the producing microorganisms.
In this respect the HKI Bio Pilot Plant offers research cooperation with external partners from academia and industry.

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